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Nature, 432(7016), 466-472

A randomized phase III trial of personalized peptide vaccination for castration-resistant prostate cancer progressing after docetaxel

Additionally, ROS can promote the recruitment and activation of immunosuppressive cells, such as regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSCs), which further inhibit the anti-tumor immune response and facilitate tumor progression [123]